Nothing protects from the pain of losing a family member to violence - not even the glitz and glamour of celebrity. These stars have all lost loved ones in unimaginable ways...

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1. Kelsey Grammer

Rex Features

Rex Features

The celebrated Frasier star has double tragedy in his past. In 1975, his sister Karen, 18, was raped and murdered by spree-killer Freddie Lee Glenn. Seven years earlier, his estranged father Frank had been shot to death.

2. Charlize Theron

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Rex Features

At the age of 15, Oscar-winning actress Charlize Theron witnessed her mother Gerda fatally shoot her abusive, alcoholic father Charles after he threatened to murder them both. Her mother faced no charges as the shooting was judged to be in self-defence.

3. Jennifer Hudson

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Rex Features

Three years after Jennifer Hudson rose to fame having reached the finals of American Idol, she was collecting an Oscar for her performance in Dream Girls. A year later, in October 2008, Hudson’s mother Darnell, brother Jason and 7-year-old nephew Julian were murdered by her former brother-in-law William Balfour. He is serving life in jail.

4. Mark Ruffalo

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Rex Features

Avengers star Mark Ruffalo was left devastated by the murder of his brother Scott in December 2008. Scott was found with a shotgun wound to the head at his LA home and died in hospital eight days later. The case remains unsolved.

5. Dave Navarro

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Rex Features

Dave Navarro found fame in the 1990s as a member of American rock band Jane’s Addiction. His mother Connie was shot to death in 1983, when Navarro was just 15. Her boyfriend, John Riccardi, was convicted of the murder in 1994, after more than a decade on the run.

6. Sofia Vergara

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Rex Features

Modern Family’s Sofia Vergara lost her brother in 1996. Rafael Jose Vergara, 26, was gunned down in their native Columbia. His killers have never been brought to justice.

7 and 8. Venus and Serena Williams

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Rex Features

Tennis superstars Venus and Serena Williams were left grieving their half-sister, Yetunde Price, 31, when she became the victim of a drive-by shooting in 2003. Reputed gang member Robert Edward Maxfield was sentenced to 15 years for the crime.